E-mail:  lhlyunnan91@163.com
Education and Professional Appointments:
2021.08 - Present: Research Associate, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming, Yunnan, China
2019.09 - 2021.06: Visiting student, The University of Texas Health Science Center at Houston, Texas, USA
2017.09 - 2021.07: Ph.D., School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China
2014.09 - 2017.07: M.S., Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China
2010.09 - 2014.07: B.S., School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China
Publication:
1. Li H-L#, Feng Y-R#, Chen Z-Y, Jiang X, Zhou Z-Y, Yuan J-F, Li F, Zhang Y, Huang X-Y,  Fan S-J*, Wu X-J*, Huang C*. 2021.
Pepper component 7-ethoxy-4-methylcoumarin, a novel dopamine D2 receptor agonist, ameliorates experimental Parkinson's disease in mice and Caenorhabditis elegans. 
Pharmacological Research, 163: 105220. 

2. Li H-L, Liu Y-L, Liu C-H, Luo L-L, Yao Y, Li F, Yin L-F, Xu L, Tong Q-C, Huang C, Fan S-J*. 2019.
Notoginsenoside Fe suppresses diet induced obesity and activates paraventricular hypothalamic neurons. 
RSC advances, 9: 1290. 

3. Li H-L, Wang P, Huang F, Jin J-M, Wu H, Zhang B-B, Wang Z-F, Shi H-L*, Wu X-J*. 2018.
Astragaloside IV protects blood-brain barrier integrity from LPS-induced disruption via activating Nrf2 antioxidant signaling. 
Toxicology and Applied Pharmacology, 340:58-66.

4. Li H-L, Jin J-M, Yang C, Wang P, Huang F, Wu H, Zhang B-B, Shi H-L*, Wu X-J*. 2018.
Isoastragaloside I suppresses LPS-induced tight junction disruption and monocyte adhesion on bEnd.3 cells via an activating Nrf2 antioxidant defense system. 
RSC advances, 8: 464-471. 

5. Li H-L#, Lu L#, Wang X-S, Qin L-Y, Wang P, Qiu S-P, Wu H, Huang F, Zhang B-B, Shi H-L*, Wu X-J*. 2017.
Alteration of Gut Microbiota and Inflammatory Cytokine/Chemokine Profiles in 5-Fluorouracil Induced Intestinal Mucositis.
Frontiers in Cellular and Infection Microbiolog, 7: 455.

6. Li H-L, Wu H, Zhang B-B, Shi H-L*, Wu X-J*. 2016.
MAPK pathways are involved in the inhibitory effect of berberine hydrochloride on gastric cancer MGC 803 cell proliferation and IL-8 secretion in vitro and in vivo. 
Molecular Medicine Reports, 14: 1430-1438.

7. Fan S-J, Xu Y-Z, Lu Y-G, Jiang Z-Y, Li H-L, Morrill J, Cai J, Wu Q, Xu Y, Xue M-S,  Arenkiel B, Huang C*, Tong Q-C*. 2021.
A neural basis for brain leptin action on reducing type 1 diabetic hyperglycemia. 
Nature Communications, 12: 2662.

8. Landry T, Li P-X, Shookster D, Jiang Z-Y, Li H-L, Laing B-T, Bunner W, Langton T, Tong Q-C, Huang H*. 2021.
Centrally circulating -klotho inversely correlates with human obesity and modulates arcuate cell population in mice. 
Molecular Metabolism, 44: 101136.

9. Liu C-H, Li H-L, Zhou Z-Y, Li J-X, Chen H, Liu Y-L, Huang C, Fan S-J*. 2019.
Protopanaxadiol alleviates obesity in hfat diet-fed mice via activation of energy-sensing neurons in the paraventricular nucleus of hypothalamus. 
Biochemical and Biophysical Research Communications, 513(4): 1092-1099.

10. Zhang W, Liu M, Yang L, Huang F, Lan Y-Y, Li H-L, Wu H, Zhang B-B, Shi H-L*, Wu X-J*. 2019.
P-glycoprotein inhibitor tariquidar potentiates efficacy of astragaloside IV in experiment autoimmune encephalomyelitis mice. 
Molecules, 24(3): 561.
Hobby: traveling, listen to music, reading, eating, cooking