E-mail:  lhlyunnan91@163.com
Education and Professional Appointments:
2021.08 - Present: Research Associate, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming, Yunnan, China
2019.09 - 2021.06: Visiting student, The University of Texas Health Science Center at Houston, Texas, USA
2017.09 - 2021.07: Ph.D., School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China
2014.09 - 2017.07: M.S., Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China
2010.09 - 2014.07: B.S., School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China
Publication:
First author (#) and Corresponding author (*):
1. Li HL#, Wang F#, Zhou ZY#, Jiang X, Li Fei, Feng YR, Liu CH, Zhang Y, Fan SJ, Wu XJ*, Huang C*. 2022. 
   Atractylon, a novel dopamine 2 receptor agonist, ameliorates Parkinsonian like motor dysfunctions in MPTP-induced mice. 
   Neurotoxicology, 89:121-126.

2. Li HL#, Feng YR#, Chen ZY, Jiang X, Zhou ZY, Yuan JF, Li F, Zhang Y, Huang XY,  Fan SJ*, Wu XJ*, Huang C*. 2021.
   Pepper component 7-ethoxy-4-methylcoumarin, a novel dopamine D2 receptor agonist, ameliorates experimental Parkinson's disease in mice and Caenorhabditis elegans. 
   Pharmacological Research, 163: 105220. 

3. Li HL#, Liu YL, Liu CH, Luo LL, Yao Y, Li F, Yin LF, Xu L, Tong QC, Huang C, Fan SJ*. 2019. 
   Notoginsenoside Fe suppresses diet induced obesity and activates paraventricular hypothalamic neurons. 
   RSC advances, 9(3): 1290-1298. 

4. Li HL#, Wang P, Huang F, Jin JM, Wu H, Zhang BB, Wang ZF, Shi HL*, Wu XJ*. 2018. 
   Astragaloside IV protects blood-brain barrier integrity from LPS-induced disruption via activating Nrf2 antioxidant signaling. 
   Toxicology and Applied Pharmacology, 340:58-66.

5. Li HL#, Jin JM, Yang C, Wang P, Huang F, Wu H, Zhang BB, Shi HL*, Wu XJ*. 2018. 
   Isoastragaloside I suppresses LPS-induced tight junction disruption and monocyte adhesion on bEnd.3 cells via an activating Nrf2 antioxidant defense system. 
   RSC advances, 8(1): 464-471. 

6. Li HL#, Lu L#, Wang XS, Qin LY, Wang P, Qiu SP, Wu H, Huang F, Zhang BB, Shi HL*, Wu XJ*. 2017. 
   Alteration of Gut Microbiota and Inflammatory Cytokine/Chemokine Profiles in 5-Fluorouracil Induced Intestinal Mucositis.
   Frontiers in Cellular and Infection Microbiolog, 7: 455.

7. Li HL#, Wu H, Zhang BB, Shi HL*, Wu XJ*. 2016. 
   MAPK pathways are involved in the inhibitory effect of berberine hydrochloride on gastric cancer MGC 803 cell proliferation and IL-8 secretion in vitro and in vivo. 
   Molecular Medicine Reports, 14: 1430-1438.
   
Others:
1. Fan SJ#, Xu YZ#, Lu YG, Jiang ZY, Li HL, Morrill J, Cai J, Wu Q, Xu Y, Xue MS,  Arenkiel B, Huang C*, Tong QC*. 2021.
    A neural basis for brain leptin action on reducing type 1 diabetic hyperglycemia. 
	Nature Communications, 12: 2662.

2. Landry T#, Li PX, Shookster D, Jiang ZY, Li HL, Laing BT, Bunner W, Langton T, Tong QC, Huang H*. 2021. 
    Centrally circulating -klotho inversely correlates with human obesity and modulates arcuate cell population in mice. 
    Molecular Metabolism, 44: 101136.

3. Liu CH#, Li HL, Zhou ZY, Li JX, Chen H, Liu YL, Huang C, Fan SJ*. 2019.
   Protopanaxadiol alleviates obesity in hfat diet-fed mice via activation of energy-sensing neurons in the paraventricular nucleus of hypothalamus. 
   Biochemical and Biophysical Research Communications, 513(4): 1092-1099.

4.   Zhang W#, Liu M, Yang L, Huang F, Lan YY, Li HL, Wu H, Zhang BB, Shi HL*, Wu XJ*. 2019. 
    P-glycoprotein inhibitor tariquidar potentiates efficacy of astragaloside IV in experiment autoimmune encephalomyelitis mice. 
       Molecules, 24(3): 561.

Hobby: traveling, listen to music, reading, eating, cooking